| Phase 1 - Selection of compound | Start | Finish | Costs(£) |
|---|---|---|---|
| 1. Chemistry – synthesis and characterisation | M1 | M10 | 86k |
| 2. Device range-findig study-separation perfomance | M2 | M4 | 81k |
| 3. Activation – selection, dose/response, duration | M4 | M12 | 198k |
| TOTAL | 365k | ||
| Phase 2 - Optimisation | Start | Finish | Costs(£) |
|---|---|---|---|
| 1. Device development (required for clinical trial) | M2 | M16 | 1,014K |
| 2. Mouse IVF – fertilisation effect | M8 | M13 | 162K |
| 3. Chemistry – GMP batch (required for clinical trial) | M11 | M16 | 139K |
| 4. Human egg sharing – effect on embryo | M12 | M18 | 480K |
| TOTAL | 1,795k | ||
| Phase 3 - Clinical trials & Approval | Start | Finish | Costs (£) |
|---|---|---|---|
| 1. Phase 3 clinical trial (required for regulatory approval) | M13 | M33 | 3,465K |
| 2. Preparation of regulatory submission & approvals | M7 | M39 | 162K |
| TOTAL | 3,627k | ||